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    1. 技術支持

      高分文獻集錦

      來源期刊:未知    ALL

      A novel platform using homobifunctional hydrazide for enrichment and isolation of urinary circulating RNAs

      來源期刊:Bioengineering & Translational Medicine    mimics

      E2F2 promotes lung adenocarcinoma progression through B-Myb- and FOXM1-facilitated core transcription regulatory circuitry

      來源期刊:International Journal of Biological Sciences    

      RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma

      來源期刊:International Journal of Biological Sciences    

      Adiponectin/AdiopR1 signaling prevents mitochondrial dysfunction and oxidative injury after traumatic brain injury in a SIRT3 dependent manner

      來源期刊:Redox Biology    干擾腺病毒載體

      The m6A reader YTHDF3-mediated PRDX3 translation alleviates liver fibrosis

      來源期刊:Redox Biology    pcDNA3.1 vector

      circPDE5A regulates prostate cancer metastasis via controlling WTAP-dependent N6-methyladenisine methylation of EIF3C mRNA

      來源期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH    siRNAs

      NCAPD3 enhances Warburg effect through c-myc and E2F1 and promotes the occurrence and progression of colorectal cancer

      來源期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH    siRNAs

      Essential role for STAT3/FOXM1/ATG7 signaling-dependent autophagy in resistance to Icotinib

      來源期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH    siRNAs

      Upregulating microRNA-210 to Inhibit Apoptosis of Neural Stem Cells with an MRI–Visible Nanomedicine for Stroke Therapy

      來源期刊:Small Structures    

      Terbinafine prevents colorectal cancer growth by inducing dNTP starvation and reducing immune suppression

      來源期刊:MOLECULAR THERAPY    siRNA

      TFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis

      來源期刊:EMBO JOURNAL    siRNAs,LV

      ZDHHC18 negatively regulates cGAS-mediated innate immunity through palmitoylation

      來源期刊:EMBO JOURNAL    siRNAs

      Arterial cyclic stretch regulates Lamtor1 and promotes neointimal hyperplasia via circSlc8a1/miR-20a-5p axis in vein grafts

      來源期刊:Theranostics    siRNAs

      MiR-155 deficiency protects renal tubular epithelial cells from telomeric and genomic DNA damage in cisplatin-induced acute kidney injury

      來源期刊:Theranostics    FISH probes

      Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR-135b-3p/TOX3 axis

      來源期刊:JOURNAL OF PINEAL RESEARCH    FISH kit

      Regulation of mesenchymal stem cell osteogenic potential via microfluidic manipulation of microcarrier surface curvature

      來源期刊:CHEMICAL ENGINEERING JOURNAL    siRNAs

      A novel microRNA, novel-m009C, regulates methamphetamine rewarding effects

      來源期刊:MOLECULAR PSYCHIATRY    probe

      Nanoparticle delivery of miR-21-3p sensitizes melanoma to anti-PD-1 immunotherapy by promoting ferroptosis

      來源期刊:Journal for ImmunoTherapy of Cancer    熒光素酶報告載體、空載

      GATA3/long noncoding RNA MHC-R regulates the immune activity of dendritic cells in chronic obstructive pulmonary disease induced by air pollution particulate matter

      來源期刊:JOURNAL OF HAZARDOUS MATERIALS    LV,siRNAs

      Bile duct ligation differently regulates protein expressions of organic cation transporters in intestine, liver and kidney of rats through activation of farnesoid X receptor by cholate and bilirubin

      來源期刊:Acta Pharmaceutica Sinica B    siRNA

      Schisandrol A protects AGEs-induced neuronal cells death by allosterically targeting ATP6V0d1 subunit of V-ATPase

      來源期刊:Acta Pharmaceutica Sinica B    siRNAs

      The genomic landscape of cholangiocarcinoma reveals the disruption of post-transcriptional modifiers

      來源期刊:Nature Communications    siRNAs

      Hierarchical Accumulation of Histone Variant H2A.Z Regulates Transcriptional States and Histone Modifications in Early Mammalian Embryos

      來源期刊:Advanced Science    siRNAs

      Dynamic Chromatin States Coupling with Key Transcription Factors in Colitis-Associated Colorectal Cancer

      來源期刊:Advanced Science    siRNAs

      ARID1A loss derepresses a group of human endogenous retrovirus-H loci to modulate BRD4-dependent transcription

      來源期刊:Nature Communications    siRNAs

      circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop

      來源期刊:Molecular Cancer    siRNAs

      METTL3 inhibits anti-tumor immunity by targeting m6A-BHLHE41-CXCL1/CXCR2 axis to promote colorectal cancer

      來源期刊:GASTROENTEROLOGY    siRNA

      Cell fate determining molecular switches and signaling pathways in Pax7-expressing somitic mesoderm

      來源期刊:Cell Discovery    siRNA

      CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m6A-modified CREB1 mRNA

      來源期刊:Molecular Cancer    FISH probes

      circFBXO7/miR-96-5p/MTSS1 axis is an important regulator in the Wnt signaling pathway in ovarian cancer

      來源期刊:Molecular Cancer    siRNAs

      Therapeutic nucleus-access BNCT drug combined CD47-targeting gene editing in glioblastoma

      來源期刊:Journal Of Nanobiotechnology    質粒

      Visualization of the process of a nanocarrier-mediated gene delivery: stabilization, endocytosis and endosomal escape of genes for intracellular spreading

      來源期刊:Journal Of Nanobiotechnology    siRNA

      PINK1/TAX1BP1-directed mitophagy attenuates vascular endothelial injury induced by copper oxide nanoparticles

      來源期刊:Journal Of Nanobiotechnology    siRNA

      Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM

      來源期刊:Journal Of Nanobiotechnology    siRNAs

      Multifunctional nanoparticles co-loaded with Adriamycin and MDR-targeting siRNAs for treatment of chemotherapy-resistant esophageal cancer

      來源期刊:Journal Of Nanobiotechnology    siRNA

      The proteasome-dependent degradation of ALKBH5 regulates ECM deposition in PM2.5 exposure-induced pulmonary fibrosis of mice

      來源期刊:Journal Of Hazardous Materials    miRNA mimic

      ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis

      來源期刊:Cell Discovery    siRNA

      Tumor bud-derived CCL5 recruits fibroblasts and promotes colorectal cancer progression via CCR5-SLC25A24 signaling

      來源期刊:Journal Of Experimental & Clinical Cancer Research    siRNAs

      PPP1R26 drives hepatocellular carcinoma progression by controlling glycolysis and epithelial-mesenchymal transition

      來源期刊:Journal Of Experimental & Clinical Cancer Research    siRNAs

      PABPC1-induced stabilization of IFI27 mRNA promotes angiogenesis and malignant progression in esophageal squamous cell carcinoma through exosomal miRNA-21-5p

      來源期刊:Journal Of Experimental & Clinical Cancer Research    siRNAs

      Cholesterol sensor SCAP contributes to sorafenib resistance by regulating autophagy in hepatocellular carcinoma

      來源期刊:Journal Of Experimental & Clinical Cancer Research    siRNA

      Histone methyltransferase Smyd2 contributes to blood-brain barrier breakdown in stroke

      來源期刊:Clinical and Translational Medicine    siRNA

      AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages

      來源期刊:Theranostics    siRNAs

      SSBP1 drives high fructose-induced glomerular podocyte ferroptosis via activating DNA-PK/p53 pathway

      來源期刊:Redox Biology    PCR引物, siRNA

      Blood exosomes-based targeted delivery of cPLA2 siRNA and metformin to modulate glioblastoma energy metabolism for tailoring personalized therapy

      來源期刊:Neuro-Oncology    

      TNF-α stimulation enhances the neuroprotective effects of gingival MSCs derived exosomes in retinal ischemia-reperfusion injury via the MEG3/miR-21a-5p axis

      來源期刊:Biomaterials    antagomir

      mTORC1 induces plasma membrane depolarization and promotes preosteoblast senescence by regulating the sodium channel Scn1a

      來源期刊:Bone Research    siRNAs

      The PCK2-glycolysis axis assists three-dimensional-stiffness maintaining stem cell osteogenesis

      來源期刊:Bioactive Materials    干擾慢病毒

      Up-regulated YB-1 protein promotes glioblastoma growth through an YB-1/CCT4/mLST8/mTOR pathway

      來源期刊:Journal Of Clinical Investigation    RNA decoys

      A CGA/EGFR/GATA2 positive feedback circuit confers chemoresistance in gastric cancer

      來源期刊:Journal Of Clinical Investigation    siRNAs

      An enhancer variant at 16q22.1 predisposes to hepatocellular carcinoma via regulating PRMT7 expression

      來源期刊:Nature Communications    siRNAs

      Secondary structure prediction for RNA sequences including N6-methyladenosine

      來源期刊:Nature Communications    RNA phosphoramidites

      RNA G-quadruplex in TMPRSS2 reduces SARS-CoV-2 infection

      來源期刊:Nature Communications    RNA oligonucleotides

      Ubiquitin ligase E3 HUWE1/MULE targets transferrin receptor for degradation and suppresses ferroptosis in acute liver injury

      來源期刊:Cell Death And Differentiation    

      Regulation of Semaphorin3A in the process of cutaneous wound healing

      來源期刊:Cell Death And Differentiation    ADV質粒載體

      TET2 regulates osteoclastogenesis by modulating autophagy in OVX-induced bone loss

      來源期刊:Autophagy    LV,siRNA

      Engineered EGCG-Containing Biomimetic Nanoassemblies as Effective Delivery Platform for Enhanced Cancer Therapy

      來源期刊:Advanced Science    siRNA

      RNF115 Inhibits the Post-ER Trafficking of TLRs and TLRs-Mediated Immune Responses by Catalyzing K11-Linked Ubiquitination of RAB1A and RAB13

      來源期刊:Advanced Science    siRNAs

      Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity

      來源期刊:Nucleic Acids Research    siRNAs

      Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

      來源期刊:Molecular Cell    siRNA

      Tumour-derived extracellular vesicle membrane hybrid lipid nanovesicles enhance siRNA delivery by tumour-homing and intracellular freeway transportation

      來源期刊:Journal of Extracellular Vesicles    siRNA

      Circ-ZEB1 promotes PIK3CA expression by silencing miR-199a-3p and affects the proliferation and apoptosis of hepatocellular carcinoma

      來源期刊:Molecular Cancer    miRNA mimic,FISH kit

      Reversible phase separation of HSF1 is required for an acute transcriptional response during heat shock

      來源期刊:Nature Cell Biology    siRNA

      Recycling of autophagosomal components from autolysosomes by the recycler complex

      來源期刊:Nature Cell Biology    siRNA

      Local hyperthermia therapy induces browning of white fat and treats obesity

      來源期刊:Cell    siRNA

      吉瑪基因2021年11月高分文獻

      來源期刊:1    

      2020-siRNA文獻

      來源期刊:    

      2020-lentivirus文獻

      來源期刊:    

      2018-siRNA Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation

      來源期刊:    

      2018-siRNA PCR kit Hyperglycaemia-induced miR-301a promotes cell proliferation by repressing p21 and Smad4 in prostate cancer

      來源期刊:    

      2018-siRNA Lysosomal deposition of copper oxide nanoparticles triggers HUVEC cells death

      來源期刊:    

      2018-LncRNA NCK1-AS1 promotes proliferation and induces cell progression by crosstalk NCK1-AS1 miR-6857 CDK1 pathway

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      2018-siRNA A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption

      來源期刊:    

      2018-LV The histone demethylase KDM6B regulates temperature-dependent sex determination in a turtle species

      來源期刊:    

      2017-Bioreducible Cross-Linked Hyaluronic Acid Calcium Phosphate Hybrid Nanoparticles for Specific Delivery of siRNA in Melanoma Tumor Therapy

      來源期刊:    

      2017 Combining Fluorination and Bioreducibility for Improved siRNA Polyplex Delivery

      來源期刊:    

      2016-NudC regulates actin dynamics and ciliogenesis by stabilizing cofilin 1

      來源期刊:    

      2015-PAQR3 modulates cholesterol homeostasis by anchoring Scap SREBP complex to the Golgi apparatus

      來源期刊:    

      2015-nature communications-APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p (antagomir)

      來源期刊:    

      2015-miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program

      來源期刊:    

      2015-Journal of Hepatology

      來源期刊:    

      2014-Nat Cell Biol-FHOD1 interaction with nesprin-2G mediates TAN line formation and nuclear movement

      來源期刊:    

      2014-Fragile X mental retardation protein stimulates ribonucleoprotein assembly of influenza A virus

      來源期刊:    

      2014-Cancer Res-miR-483-5p promotes invasion and metastasis of lung adenocarcinoma by targeting RhoGDI1 and ALCAM

      來源期刊:    

      2013-Switch of glycolysis to gluconeogenesis by dexamethasone for treatment of hepatocarcinoma

      來源期刊:    

      2013-Nature biotechnology-Efficient and specific gene knockdown by small interfering RNAs produced in bacteria

      來源期刊:    

      2012-cell research-Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice (antagomir)

      來源期刊:    

      2011-Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowth

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